When a former member of NERDS turns into a villainous cheerleader, Matilda "Wheezer" Choi and the rest of the NERDS must infiltrate the cheerleader squad and save the world from a machine that wreaks havoc by entering other dimensions.
Led by Duncan "Gluestick" Dewey, the NERDS team uses brain power and courage rather than gadgets when they face off against supervillian Simon, his band of savage squirrels, and Albert, a middle-aged computer genius who lives with his mother.
When the fairy-tale detectives rush to New York City hoping to find an Everafter who can cure Puck, they trigger a chain of events that includes a murder mystery, and learn many new things about their mother who, along with their father, is still in an enchanted sleep.